Custom DNA Oligos
We streamline primer selection for our customers by meticulously evaluating products based on essential criteria: purification technique, application suitability, synthesis duration, affordability, and further specifications, guaranteeing the best match for their unique research requirements.
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Conventional primers
Length: 10-60 bases
Purification: Desalt, HPLC, PAGE
Quantity: 2/5/10/50/100 OD
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Long chain primers 1
Length: 61-80 bases
Purification: Desalt, PAGE
Quantity: 1/2/5 OD
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Long chain primers 2
Length: 81-100 bases
Purification: PAGE
Quantity: 1 OD
Purification Options
Desalt
- Applicable length: 10-90 bases
- Application(s): PCR, Sanger sequencing, Gene synthesis; Meets most molecular biology laboratory needs.
PAGE
- Applicable length: 10-100 bases
- Application(s): PCR, Sanger sequencing, Gene synthesis, mutant subclone, gene construct, Better for long chain primer purification.
HPLC
- Applicable length: ~60 bases
- Application(s): PCR, Sanger sequencing, Gene synthesis, mutant subclone, gene construct, Antisense, modified primer; Application to purification of primers and probes for commercial diagnostic kits.
PAGE+HPLC
- Applicable length: 10-100 bases
- Application(s): PCR, Sanger sequencing, Gene synthesis, mutant subclone, gene construct, Antisense, modified primer; Suitable for long fragments and products that require increased purity
NOTE:
1. Desalt, Oligos are processed through normal-phase chromatography column, which removes salts but not failure sequences;
2. PAGE, Polyacrylamide gel electrophoresis (PAGE) is a method used to differentiate full-length product from failure sequences based on size and conformadtion.
This method removes short-stranded primers from the synthesis and works very well for long-stranded primers (>60 bases).
3. HPLC, Reverse-phase high-performance liquid chromatography (HPLC) removes failure sequences or unincorporated labels the same way as cartridge purification. The method achieves high purity and sensitivity when used for isolation and purification or analysis. It works very well for purification of modified primers.